Cagrilintide Semaglutide Blend 10mg/10mg

Description

The Cagrilintide Semaglutide blend 10mg from Polaris Peptides holds 10mg Cagrilintide and 10mg Semaglutide, freeze-dried together in one vial. It’s sold for laboratory research only.

What the Cagrilintide Semaglutide blend 10mg contains

Cagrilintide is a long-acting amylin analog from Novo Nordisk, given weekly. Amylin is a hormone released with insulin that slows stomach emptying and reduces appetite.

Semaglutide is a GLP-1 receptor agonist developed by Novo Nordisk. A fatty acid chain lets it bind albumin, which gives it a half-life of about a week.

Pairing a long-acting amylin analog with a GLP-1 agonist is the idea behind CagriSema, which Novo Nordisk tested in the REDEFINE trials. The REDEFINE 1 results, published in the New England Journal of Medicine in 2025, reported average weight loss of about 20% at 68 weeks.

The vial holds 10mg cagrilintide and 10mg semaglutide, 20mg in total. Because everything is freeze-dried together, the ratio can’t drift the way it can when you mix separate vials. One reconstitution, one label, the same proportions in every draw.

How the Cagrilintide Semaglutide blend 10mg works

Amylin is released by the pancreas together with insulin. It slows stomach emptying, damps glucagon after meals and signals fullness through the brainstem.

GLP-1 is a gut hormone released after a meal. It tells the pancreas to release insulin, but only when blood sugar is high, and it slows how fast the stomach empties. Receptors in the hypothalamus pick it up too, which is where its effect on appetite comes from.

Cagrilintide Semaglutide blend 10mg technical data

• Cagrilintide, 10mg: CAS 1415456-99-3, 4,409 g/mol
• Semaglutide, 10mg: CAS 910463-68-2, C187H291N45O59, 4,113.6 g/mol
• Amount: 20mg in total (10mg/10mg per vial)
• Form: lyophilized (freeze-dried) powder
• Purity: over 99% (HPLC-MS)
• Packaging: vacuum-sealed
• SKU: PP-CAGSEMA-20
• Use: laboratory research only

Cagrilintide Semaglutide blend research

Enebo and colleagues reported in The Lancet (2021) that cagrilintide with semaglutide gave more weight loss than either alone.

Phase 3 REDEFINE trials followed.

The STEP 1 trial (New England Journal of Medicine, 2021) reported average weight loss of about 15% over 68 weeks.

The SELECT trial reported fewer major cardiovascular events.

For the original studies, try this PubMed search.

Reconstituting Cagrilintide Semaglutide blend 10mg

Here’s the math for 20mg of powder:

• 1mL of bacteriostatic water gives 20mg/mL
• 2mL of bacteriostatic water gives 10mg/mL
• 3mL of bacteriostatic water gives 6.67mg/mL

Choose the volume that suits your measurements. Mark the vial with the concentration and date so nobody has to guess later.

Bacteriostatic water is the usual choice. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.

Cagrilintide Semaglutide blend 10mg storage and shelf life

Store sealed vials of Cagrilintide Semaglutide blend 10mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within 28 days.

Let a frozen vial warm up to room temperature before you open it. Cold glass pulls moisture out of the air, and that moisture is what degrades dry peptide.

Cagrilintide Semaglutide blend 10mg purity and lab testing

Cagrilintide Semaglutide blend 10mg goes through HPLC-MS before it’s sold. Chromatography gives the purity figure, and the mass spectrometer checks the molecular weight against the expected value. Cagrilintide Semaglutide blend 10mg tests at over 99% purity.

The vials are vacuum-sealed once the powder is freeze-dried. Moisture and oxygen are the two things that break down dry peptide fastest, and the seal keeps both out.

If you run a long study, try to keep it on one batch and log the number from the label. It removes one variable from your results.

Cagrilintide Semaglutide blend sizes compared

• Cagrilintide Semaglutide Blend 3mg/3mg: $50.00, about $8.33 per mg
• Cagrilintide Semaglutide Blend 10mg/10mg (this page): $149.00, about $7.45 per mg

For longer projects a larger vial like Cagrilintide Semaglutide blend 10mg means fewer vials to mix and fewer reorders.

Often ordered with Cagrilintide Semaglutide blend 10mg

• Tirzepatide 60mg, a GIP/GLP-1 agonist
• Retatrutide 10mg, a triple agonist
• Cagrilintide 5mg, an amylin analog
• Semaglutide 5mg, a GLP-1 agonist
• Survodutide 5mg, a GLP-1/glucagon agonist

Browse the full GLP-1 peptides and weight loss peptides range, or see every product on our research peptides page.

Common questions about Cagrilintide Semaglutide blend 10mg

How much is in the Cagrilintide Semaglutide blend 10mg vial?

10mg of Cagrilintide and 10mg of Semaglutide, freeze-dried together. The amount is printed on the label.

Is Cagrilintide Semaglutide blend 10mg in stock?

Yes. Cagrilintide Semaglutide blend 10mg is in stock and ready to ship.

How pure is Cagrilintide Semaglutide blend 10mg?

Over 99% by HPLC-MS. The same test confirms the molecular weight, so it checks identity too.

What do I mix Cagrilintide Semaglutide blend 10mg with?

Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.

How should I store it?

Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within 28 days.

Order Cagrilintide Semaglutide blend 10mg today

Order Cagrilintide Semaglutide blend 10mg now for $149.00. It’s in stock, and checkout takes about two minutes.

Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.

For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.