Description
The Cagrilintide Semaglutide blend 3mg from Polaris Peptides holds 3mg Cagrilintide and 3mg Semaglutide, freeze-dried together in one vial. It’s sold for laboratory research only.
What’s in the Cagrilintide Semaglutide blend 3mg?
Cagrilintide is a long-acting amylin analog from Novo Nordisk, given weekly. Amylin is a hormone released with insulin that slows stomach emptying and reduces appetite.
Semaglutide is a GLP-1 receptor agonist developed by Novo Nordisk. A fatty acid chain lets it bind albumin, which gives it a half-life of about a week.
Pairing a long-acting amylin analog with a GLP-1 agonist is the idea behind CagriSema, which Novo Nordisk tested in the REDEFINE trials. The REDEFINE 1 results, published in the New England Journal of Medicine in 2025, reported average weight loss of about 20% at 68 weeks.
The vial holds 3mg cagrilintide and 3mg semaglutide, 6mg in total. Because everything is freeze-dried together, the ratio can’t drift the way it can when you mix separate vials. One reconstitution, one label, the same proportions in every draw.
How the Cagrilintide Semaglutide blend 3mg works
Amylin is released by the pancreas together with insulin. It slows stomach emptying, damps glucagon after meals and signals fullness through the brainstem.
GLP-1 is a gut hormone released after a meal. It tells the pancreas to release insulin, but only when blood sugar is high, and it slows how fast the stomach empties. Receptors in the hypothalamus pick it up too, which is where its effect on appetite comes from.
Cagrilintide Semaglutide blend 3mg technical data
- Cagrilintide, 3mg: CAS 1415456-99-3, 4,409 g/mol
- Semaglutide, 3mg: CAS 910463-68-2, C187H291N45O59, 4,113.6 g/mol
- Amount: 6mg in total (3mg/3mg per vial)
- Form: lyophilized (freeze-dried) powder
- Purity: over 99% (HPLC-MS)
- Packaging: vacuum-sealed
- SKU: PP-CAGSEMA-6
- Use: laboratory research only
What the research says about Cagrilintide Semaglutide blend
Enebo and colleagues reported in The Lancet (2021) that cagrilintide with semaglutide gave more weight loss than either alone.
Phase 3 REDEFINE trials followed.
The STEP 1 trial (New England Journal of Medicine, 2021) reported average weight loss of about 15% over 68 weeks.
The SELECT trial reported fewer major cardiovascular events.
The primary literature is on PubMed. Here’s a search for Cagrilintide and Semaglutide studies to start from.
How Cagrilintide Semaglutide blend 3mg is tested
Every batch of Cagrilintide Semaglutide blend 3mg is checked by HPLC-MS. HPLC separates the sample and measures how much of it is the target compound, and mass spectrometry confirms the molecular weight, so one test covers both purity and identity. Cagrilintide Semaglutide blend 3mg tests at over 99% purity.
The vials are vacuum-sealed once the powder is freeze-dried. Moisture and oxygen are the two things that break down dry peptide fastest, and the seal keeps both out.
If you run a long study, try to keep it on one batch and log the number from the label. It removes one variable from your results.
How to reconstitute Cagrilintide Semaglutide blend 3mg
Here’s the math for 6mg of powder:
- 1mL of bacteriostatic water gives 6mg/mL
- 2mL of bacteriostatic water gives 3mg/mL
- 3mL of bacteriostatic water gives 2mg/mL
Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.
Bacteriostatic water is the usual choice. Add it slowly so it runs down the side of the vial, then swirl or roll until everything dissolves. Shaking can shear peptide chains. Skip it.
How to store Cagrilintide Semaglutide blend 3mg
Store sealed vials of Cagrilintide Semaglutide blend 3mg in the freezer at -20°C, out of direct light. Mixed solution goes in the fridge at 2 to 8°C and should be used within 28 days.
Let a frozen vial warm up to room temperature before you open it. Cold glass pulls moisture out of the air, and that moisture is what degrades dry peptide.
Choosing a Cagrilintide Semaglutide blend strength
- Cagrilintide Semaglutide Blend 3mg/3mg (this page): $50.00, about $8.33 per mg
- Cagrilintide Semaglutide Blend 10mg/10mg: $149.00, about $7.45 per mg
Cagrilintide Semaglutide blend 3mg is the smallest size. It’s the one to start with for a pilot run or when you’re testing a new protocol.
Often ordered with Cagrilintide Semaglutide blend 3mg
- Semaglutide 10mg, a GLP-1 agonist
- Cagrilintide 10mg, an amylin analog
- Retatrutide 35mg, a triple agonist
- Tirzepatide 50mg, a GIP/GLP-1 agonist
- Survodutide 5mg, a GLP-1/glucagon agonist
Browse the full GLP-1 peptides and weight loss peptides range, or see every product on our research peptides page.
Cagrilintide Semaglutide blend 3mg questions
How much is in the Cagrilintide Semaglutide blend 3mg vial?
3mg of Cagrilintide and 3mg of Semaglutide, freeze-dried together. The amount is printed on the label.
How pure is Cagrilintide Semaglutide blend 3mg?
Over 99% by HPLC-MS. The same test confirms the molecular weight, so it checks identity too.
What do I mix Cagrilintide Semaglutide blend 3mg with?
Sterile bacteriostatic water is the usual choice. The reconstitution section above shows the concentration for each volume.
How should I store it?
Keep sealed vials in the freezer at -20°C. Once mixed, refrigerate at 2 to 8°C and use within 28 days.
Can Cagrilintide Semaglutide blend be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Order Cagrilintide Semaglutide blend 3mg today
Ready to order? Cagrilintide Semaglutide blend 3mg costs $50.00, down from $75.00 and is in stock. Add it to your cart and you’re done.
Need more for the same project? See the rest of our GLP-1 peptides and weight loss peptides.
For laboratory research use only. Not for human or veterinary use. These statements have not been evaluated by the FDA.
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