Polaris Peptides semaglutide: 2mg to 20mg
Polaris Peptides semaglutide comes in five strengths and two cagrilintide blends, over 99% pure by HPLC-MS. This guide covers the compound, the research and how to choose.

What is Polaris Peptides semaglutide?
Semaglutide is a GLP-1 receptor agonist developed by Novo Nordisk. It’s a modified version of human GLP-1 with a fatty acid chain that binds albumin, which stretches its half-life to about a week. It’s approved as Ozempic and Rybelsus for type 2 diabetes and as Wegovy for weight management.
Polaris Peptides semaglutide is the research-grade peptide, freeze-dried in vacuum-sealed vials and sold for laboratory research only.
Polaris Peptides semaglutide prices
- Semaglutide 2mg: from $30
- Semaglutide 5mg: from $50
- Semaglutide 10mg: from $90
- Semaglutide 12.5mg: from $105
- Semaglutide 20mg: from $165 (on sale)
Prices fall per milligram as the vial gets bigger: about $15 per mg for 2mg and $8.25 for 20mg. Every strength comes in packs of 2 to 20 at up to 30% off.

Semaglutide and cagrilintide blends
- Cagrilintide Semaglutide Blend 3mg/3mg: from $50 (on sale)
- Cagrilintide Semaglutide Blend 10mg/10mg: from $149
- Cagrilintide 5mg: from $80 (on sale)
- Cagrilintide 10mg: from $140
Cagrilintide is a long-acting amylin analog. Pairing it with semaglutide is the idea behind CagriSema, which Novo Nordisk tested in the REDEFINE trials. The blends put both in one vial at a fixed ratio.
What the semaglutide research found
In the STEP 1 trial, published in the New England Journal of Medicine in 2021, adults with obesity lost about 15% of body weight on average over 68 weeks. The SELECT trial later looked at heart outcomes. Follow the studies on ClinicalTrials.gov or through this PubMed search for semaglutide.
Choosing a Polaris Peptides semaglutide vial
Semaglutide 2mg and 5mg suit pilot runs. 10mg and 12.5mg are the middle ground, and 20mg is the cheapest per milligram. For comparison work, add tirzepatide or retatrutide.
Mix with sterile bacteriostatic water, added slowly down the glass. Keep sealed vials at -20°C and mixed vials in the fridge for up to 28 days.
Polaris Peptides semaglutide specifications
- Compound: semaglutide
- Type: GLP-1 receptor agonist
- Molecular formula: C187H291N45O59
- Strengths: 2mg, 5mg, 10mg, 12.5mg and 20mg per vial
- Purity: over 99% by HPLC-MS
- Packs: 2 to 20 vials, 10% to 30% off
- Use: laboratory research only
How semaglutide works
Semaglutide copies GLP-1, a gut hormone released after meals. It raises insulin release when blood sugar is high, slows the stomach and acts on appetite centers in the brainstem and hypothalamus. Two small changes to the sequence protect it from the enzyme that breaks down natural GLP-1, and the fatty acid chain keeps it in circulation for days.
It’s the reference compound in most incretin research. If you’re testing tirzepatide or retatrutide, Polaris Peptides semaglutide makes a natural comparison arm.
Calculating semaglutide concentrations
- 2mg vial + 1mL water = 2mg/mL
- 5mg vial + 2mL water = 2.5mg/mL
- 10mg vial + 2mL water = 5mg/mL
- 12.5mg vial + 2.5mL water = 5mg/mL
- 20mg vial + 4mL water = 5mg/mL
Polaris Peptides semaglutide picks at a glance
Semaglutide 2mgFrom $30
Semaglutide 5mgFrom $50
Semaglutide 20mgFrom $165
Cagrilintide Semaglutide Blend 10mg/10mgFrom $149Planning a semaglutide order
Total the amount every arm of your study needs, then pick the strength that leaves the least left over. Small totals suit the 2mg or 5mg vial. Bigger projects usually come out cheapest with several 20mg vials in a pack. Mix one vial at a time and keep the rest frozen, so nothing expires in the fridge before you use it.
Polaris Peptides semaglutide FAQ
Which Polaris Peptides semaglutide strengths are there?
Five: 2mg, 5mg, 10mg, 12.5mg and 20mg.
Do you sell semaglutide with cagrilintide?
Yes. There are two cagrilintide and semaglutide blends, 3mg/3mg and 10mg/10mg.
Which semaglutide vial is cheapest per milligram?
The 20mg vial, at about $8.25 per mg.
Is Polaris Peptides semaglutide for human use?
No. It’s sold for laboratory research only.
Related reading: Polaris Peptides tirzepatide and Polaris Peptides retatrutide.
Buy semaglutide from Polaris Peptides
Five strengths and two blends, over 99% pure and in stock.
Polaris Peptides products are sold for laboratory research use only. They aren’t for human or veterinary use and haven’t been evaluated by the FDA.
